1Wageningen University,Division of Human Nutrition,PO Box 17,6700 AA Wageningen,The Netherlands.
2Maastricht University Medical Centre+,NUTRIM School for Nutrition and Translational Research in Metabolism,Department of Human Biology and Movement Sciences,Maastricht,The Netherlands.
Public Health Nutr. 2017 Oct;20(14):2617-2628. doi: 10.1017/S1368980017001458. Epub 2017 Jul 24.
To evaluate whether the lifestyle intervention MetSLIM targeting individuals of low socio-economic status of Turkish, Moroccan and Dutch origin was successful in improving waist circumference and other cardiometabolic risk factors, lifestyle behaviour and quality of life.
A quasi-experimental intervention study (Netherlands Trial Register NTR3721). The intervention group participated in a 12-month combined dietary and physical activity programme. Examinations were performed at baseline and after 12 months. Participants underwent anthropometric measurements and blood withdrawal, and completed questionnaires on dietary intake, physical activity and quality of life.
Socio-economically deprived neighbourhoods in two Dutch cities, involving non-blinded ethnicity-matched and gender-matched research assistants, dietitians and sports instructors.
Mainly Turkish (49 %) and Dutch (36 %) subjects, aged 30-70 years, with a waist-to-height ratio of >0·5 (intervention, n 117; control, n 103). Dropout was 31 %.
At 12 months, the intervention group showed greater improvements than the control group in waist circumference (β=-3·3 cm, 95 % CI -4·7, -1·8, P<0·001) and other obesity measures. Additionally, greater reductions were observed for total cholesterol (β=-0·33 mmol/l, 95 % CI -0·56, -0·10, P=0·005) and LDL cholesterol (β=-0·35 mmol/l, 95 % CI -0·56, -0·14, P=0·001). Dietary changes were significant for fibre intake (β=1·5 g/4184 kJ (1000 kcal), 95 % CI 0·3, 2·7, P=0·016). Compared with the control group, the intervention group reported a decrease in total minutes of physical activity (β=-573 min/week, 95 % CI -1126, -21, P=0·042) and showed improvements in the quality-of-life domains 'health transition' and 'general health'.
MetSLIM was shown to be effective in improving waist circumference, total and LDL cholesterol, and quality of life among Dutch and Turkish individuals living in deprived neighbourhoods.
评估针对土耳其裔、摩洛哥裔和荷兰裔低社会经济地位个体的生活方式干预措施 MetSLIM 是否成功改善了腰围和其他心血管代谢风险因素、生活方式行为和生活质量。
一项准实验性干预研究（荷兰试验注册 NTR3721）。干预组参加了为期 12 个月的饮食和身体活动综合方案。在基线和 12 个月后进行检查。参与者接受了人体测量学测量和血液采集，并完成了关于饮食摄入、身体活动和生活质量的问卷。
涉及两个荷兰城市社会经济贫困社区的非盲匹配和性别匹配的研究助理、营养师和体育指导员。
主要为土耳其裔（49%）和荷兰裔（36%）年龄在 30-70 岁之间的个体，腰围与身高比值大于 0.5（干预组 117 人，对照组 103 人）。失访率为 31%。
在 12 个月时，与对照组相比，干预组的腰围（β=-3.3cm，95%CI-4.7，-1.8，P<0.001）和其他肥胖指标的改善更大。此外，总胆固醇（β=-0.33mmol/L，95%CI-0.56，-0.10，P=0.005）和 LDL 胆固醇（β=-0.35mmol/L，95%CI-0.56，-0.14，P=0.001）的降低更为显著。膳食纤维摄入量的变化具有统计学意义（β=1.5g/4184kJ（1000kcal），95%CI0.3，2.7，P=0.016）。与对照组相比，干预组报告每周的总身体活动分钟数减少（β=-573 分钟/周，95%CI-1126，-21，P=0.042），并且在“健康转变”和“一般健康”生活质量领域有所改善。
MetSLIM 被证明在改善生活在贫困社区的荷兰和土耳其裔个体的腰围、总胆固醇和 LDL 胆固醇以及生活质量方面是有效的。
