Müller-Riemenschneider Falk, Reinhold Thomas, Berghöfer Anne, Willich Stefan N
Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, Berlin, Germany,
Eur J Epidemiol. 2008;23(8):499-509. doi: 10.1007/s10654-008-9239-1. Epub 2008 May 29.
Although overweight and obesity have long been recognised as major risk factors for a number of chronic diseases, lifestyle developments have led to substantial increases in bodyweight worldwide. In addition to their negative effects on health and quality of life, obesity and associated comorbidities may have a considerable impact on healthcare expenditures. The aim of this systematic review was to summarise cost estimates and compare costs attributable to obesity across different European countries. A structured search in MEDLINE, EMBASE, and all EBM Reviews was conducted to identify relevant literature. Two researchers independently assessed publications according to pre-defined inclusion criteria and with regard to study methodology. Costs attributable to obesity were extracted from the included studies and calculated relative to country-specific gross domestic income. Out of 797 publications that met our search criteria, 13 studies investigating 10 Western European countries were determined to be relevant and included in our review. Obesity-related healthcare burdens of up to 10.4 billion euros were found. Reported relative economic burdens ranged from 0.09% to 0.61% of each country's gross domestic product (GDP). Obesity appears to be responsible for a substantial economic burden in many European countries, and the costs identified in the available studies presumably reflect conservative estimates. There remains a great need for prospective and standardised studies to provide more accurate estimates of costs for all European countries.
尽管超重和肥胖长期以来一直被认为是多种慢性疾病的主要风险因素,但生活方式的变化导致全球体重显著增加。除了对健康和生活质量产生负面影响外,肥胖及相关合并症可能对医疗保健支出产生重大影响。本系统评价的目的是总结成本估算,并比较不同欧洲国家肥胖所致的成本。在MEDLINE、EMBASE和所有循证医学综述中进行了结构化检索,以识别相关文献。两名研究人员根据预先定义的纳入标准并针对研究方法独立评估出版物。从纳入研究中提取肥胖所致成本,并相对于各国国内总收入进行计算。在符合我们检索标准的797篇出版物中,13项对10个西欧国家进行调查的研究被确定为相关并纳入我们的综述。发现肥胖相关的医疗负担高达104亿欧元。报告的相对经济负担占各国国内生产总值(GDP)的0.09%至0.61%。肥胖似乎在许多欧洲国家造成了巨大的经济负担,现有研究确定的成本可能反映了保守估计。仍然非常需要进行前瞻性和标准化研究,以更准确地估算所有欧洲国家的成本。