Institute of Physiology and Zürich Center for Integrative Human Physiology (ZIHP), University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland.
Biomed Eng Online. 2011 Jan 25;10:8. doi: 10.1186/1475-925X-10-8.
Computer supported, interactive e-learning systems are widely used in the teaching of physiology. However, the currently available complimentary software tools in the field of the physiology of cardiovascular mechanics have not yet been adapted to the latest systems software. Therefore, a simple-to-use replacement for undergraduate and graduate students' education was needed, including an up-to-date graphical software that is validated and field-tested.
Software compatible to Windows, based on modified versions of existing mathematical algorithms, has been newly developed. Testing was performed during a full term of physiological lecturing to medical and biology students.
The newly developed CLabUZH software models a reduced human cardiovascular loop containing all basic compartments: an isolated heart including an artificial electrical stimulator, main vessels and the peripheral resistive components. Students can alter several physiological parameters interactively. The resulting output variables are printed in x-y diagrams and in addition shown in an animated, graphical model. CLabUZH offers insight into the relations of volume, pressure and time dependency in the circulation and their correlation to the electrocardiogram (ECG). Established mechanisms such as the Frank-Starling Law or the Windkessel Effect are considered in this model. The CLabUZH software is self-contained with no extra installation required and runs on most of today's personal computer systems.
CLabUZH is a user-friendly interactive computer programme that has proved to be useful in teaching the basic physiological principles of heart mechanics.
计算机支持的交互式电子学习系统广泛应用于生理学教学。然而,目前心血管力学生理学领域的补充软件工具尚未适应最新的系统软件。因此,需要一种简单易用的替代本科生和研究生教育的工具,包括经过验证和现场测试的最新图形软件。
基于现有数学算法的修改版本,新开发了与 Windows 兼容的软件。在对医学和生物学学生进行的一整个生理学讲座学期中进行了测试。
新开发的 CLabUZH 软件模拟了一个包含所有基本腔室的简化人体心血管循环:一个包含人工电刺激器的孤立心脏、主要血管和外周阻力成分。学生可以交互式地改变几个生理参数。生成的输出变量以 x-y 图打印,并以动画图形模型显示。CLabUZH 提供了对循环中体积、压力和时间依赖性及其与心电图(ECG)的相关性的深入了解。该模型考虑了诸如 Frank-Starling 定律或 Windkessel 效应等已建立的机制。CLabUZH 软件是一个独立的软件,无需额外安装,可在当今大多数个人计算机系统上运行。
CLabUZH 是一个用户友好的交互式计算机程序,已被证明在教授心脏力学的基本生理原理方面非常有用。