Program in Nursing Science, College of Health Sciences, University of California-Irvine, CA 92697, USA.
J Cardiovasc Nurs. 2011 Sep-Oct;26(5):414-22. doi: 10.1097/JCN.0b013e3182017c1f.
The purposes of this study were to (1) describe anthropometric measures among Korean immigrants with type 2 diabetes mellitus (T2DM) and (2) examine the relationships between measures of obesity with several forms of dyslipidemia in this group.
Obesity and dyslipidemia are commonly associated with T2DM, and they are risk factors for coronary heart disease (CHD), the leading cause of death for people with diabetes. Asians are predisposed to abdominal obesity and experience significant CHD risk at lower body mass index (BMI) levels. Despite high prevalence of diabetes among Korean immigrants, relationships among anthropometric measures and lipid-related CHD risk factors have not been examined.
A convenience sample of 143 adult Korean immigrants with T2DM between the ages of 30 and 80 years participated in the study. Body mass index, waist circumference (WC), and waist-to-hip ratio (WHR) were obtained using standardized procedures. Total cholesterol, triglycerides, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol were assessed using a fingerstick blood test. Hierarchical linear regressions were conducted to identify which of the anthropometric measures was significantly related to individuals' cholesterol levels.
Central obesity measures, not BMI, were significantly associated with dyslipidemia in Korean immigrants with T2DM independent of potential confounds such as hemoglobin A1C, cigarette smoking, age, and cholesterol medication. Different central obesity measures were associated with different cholesterol types for diabetic Korean men and women. In men, WHR was positively associated with low-density lipoprotein cholesterol and total cholesterol levels. In women, WC was negatively associated with high-density lipoprotein cholesterol.
Central obesity measures (WC and WHR) are better indicators for assessing lipid-related CHD risk factor among Korean immigrants with T2DM than BMI. Gender difference in the association between central obesity measures and lipid types should be considered in CHD risk assessment of Korean immigrants with T2DM.
本研究旨在：(1)描述 2 型糖尿病 (T2DM) 韩国移民的人体测量指标；(2)在该人群中，检验肥胖指标与多种形式血脂异常之间的关系。
肥胖和血脂异常通常与 T2DM 相关，并且是冠心病 (CHD) 的危险因素，而 CHD 是糖尿病患者的主要死亡原因。亚洲人易患腹部肥胖，且在较低的体重指数 (BMI) 水平下，患 CHD 的风险显著增加。尽管韩国移民中糖尿病的患病率很高，但人体测量指标与与血脂相关的 CHD 危险因素之间的关系尚未得到研究。
本研究采用便利抽样方法，选取了 143 名年龄在 30 至 80 岁之间的患有 T2DM 的成年韩国移民作为研究对象。使用标准化程序获取 BMI、腰围 (WC) 和腰臀比 (WHR)。使用指尖采血试验评估总胆固醇、甘油三酯、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇。进行层次线性回归，以确定哪些人体测量指标与个体的胆固醇水平显著相关。
在患有 T2DM 的韩国移民中，中心性肥胖指标，而不是 BMI，与血脂异常独立相关，不受血红蛋白 A1C、吸烟、年龄和胆固醇药物等潜在混杂因素的影响。不同的中心性肥胖指标与糖尿病韩国男性和女性的不同胆固醇类型相关。在男性中，WHR 与 LDL 胆固醇和总胆固醇水平呈正相关。在女性中，WC 与高密度脂蛋白胆固醇呈负相关。
在患有 T2DM 的韩国移民中，中心性肥胖指标 (WC 和 WHR) 比 BMI 更能评估与血脂相关的 CHD 危险因素。在评估患有 T2DM 的韩国移民的 CHD 风险时，应考虑中心性肥胖指标与血脂类型之间的性别差异。
