Bird Garrett R, Libke Robert D, Billelo John F, Parks Nancy A, Pollard John S
Mcgill J Med. 2009 Nov 16;12(2):14.
Coccidioidomycosis is a dimorphic fungus endemic to the southwestern United States, Central and South America. We report a case of a previously healthy person who presented with respiratory failure and disseminated Coccidioidomycosis who eventually had a fatal outcome. Coccidioidomycosis, or "Valley Fever" has been called the "great imitator" (1) as it can have a wide variety of clinical presentations. This case is unique as it represents the first described case of an immunocompetent host with rapidly progressing, disseminated coccidioidomycosis with clinically apparent splenomegaly and hepatomegaly.
球孢子菌病是一种在美国西南部、中美洲和南美洲流行的双相真菌。我们报告一例既往健康的患者，该患者出现呼吸衰竭并患有播散性球孢子菌病，最终死亡。球孢子菌病，即“山谷热”，被称为“伟大的模仿者”(1)，因为它可以有各种各样的临床表现。该病例独特之处在于，它是首例描述的具有快速进展、播散性球孢子菌病且伴有临床明显脾肿大和肝肿大的免疫功能正常宿主的病例。
