Powner David J, Doshi Pratik B
Neurosurgery Department, University of Texas Health Science Center at Houston Medical School, 77030, USA.
Prog Transplant. 2010 Dec;20(4):401-5; quiz 406. doi: 10.1177/152692481002000414.
Monitoring oxygen saturation of blood drawn from a catheter placed within the superior vena cava (Scvo2) has recently been promoted as a substitute for evaluating oxygen saturation of mixed venous blood drawn from the pulmonary artery (Svo2). The Svo2 reflects the balance between oxygen delivery and oxygen consumption throughout the body and, among critically ill patients, may be helpful for assessing resuscitation, cardiac function, or oxygen homeostasis end points. Use of Scvo2 instead has been promoted because of its easier access and recent use during resuscitation of patients with severe infections. Although data from healthy subjects and critically ill patients are available, no study has been done among organ donors to evaluate customary values for either Scvo2 or Svo2 or how well the values correspond. After loss of oxygen consumption in the brain following brain death, the customary values for these variables may be different from values in other groups of patients. Therefore, until donor-specific normative values for these important parameters are identified, we do not recommend that Scvo2 be used to evaluate the balance between donor oxygen consumption and delivery or as a variable to guide treatment.
监测经置于上腔静脉的导管抽取的血液的氧饱和度（Scvo2），最近已被推荐作为评估经肺动脉抽取的混合静脉血氧饱和度（Svo2）的替代方法。Svo2反映了全身氧输送与氧消耗之间的平衡，对于重症患者，可能有助于评估复苏情况、心功能或氧稳态终点。而使用Scvo2替代Svo2，是因为其更容易获取，且在重症感染患者的复苏过程中已有应用。尽管已有来自健康受试者和重症患者的数据，但尚未对器官捐献者进行研究，以评估Scvo2或Svo2的常规值，以及这些值的对应程度。脑死亡后脑内氧消耗停止后，这些变量的常规值可能与其他患者群体不同。因此，在确定这些重要参数的供体特异性规范值之前，我们不建议使用Scvo2来评估供体氧消耗与输送之间的平衡，或作为指导治疗的变量。
