Institute for Bioscience and Biotechnology Research, 9600 Gudelsky Drive, Rockville, MD 20850, USA.
Biochem Soc Trans. 2011 Jan;39(1):20-4. doi: 10.1042/BST0390020.
PCNA (proliferating-cell nuclear antigen) is a ring-shaped protein that encircles duplex DNA and plays an essential role in many DNA metabolic processes. The PCNA protein interacts with a large number of cellular factors and modulates their enzymatic activities. In the present paper, we summarize the structures, functions and interactions of the archaeal PCNA proteins.
PCNA（增殖细胞核抗原）是一种环绕双链 DNA 的环形蛋白，在许多 DNA 代谢过程中发挥着重要作用。PCNA 蛋白与大量的细胞因子相互作用，并调节它们的酶活性。在本文中，我们总结了古菌 PCNA 蛋白的结构、功能和相互作用。
