Szilagyi A
Can Fam Physician. 1986 Sep;32:1938-89.
The problem of liver damage in alcoholic patients is widespread. This review discusses hepatic damage on the basis of a histologic classification of increasing severity. In the early stages, or with compensated cirrhosis, clinical and laboratory findings may not accurately reflect hepatic involvement. Furthermore, there exists a group of alcoholic patients in whom liver disease may be caused by factors other than alcohol. Nevertheless, in most patients with liver disease, certain biochemical features help to establish an alcoholic etiology. These features and the use of liver biopsy are discussed, and a practical guideline for diagnosis and follow-up is offered.
酒精性肝病患者的肝损伤问题普遍存在。本综述基于严重程度递增的组织学分类来探讨肝损伤。在早期阶段，或代偿期肝硬化时，临床和实验室检查结果可能无法准确反映肝脏受累情况。此外，有一组酒精性肝病患者，其肝脏疾病可能由酒精以外的因素引起。然而，在大多数肝病患者中，某些生化特征有助于确立酒精性病因。本文将讨论这些特征以及肝活检的应用，并提供一份实用的诊断和随访指南。
