Petersen Helle Vendel, Domanska Katarina, Bendahl Pär-Ola, Wong Jiahui, Carlsson Christina, Bernstein Inge, Esplen Mary Jane, Nilbert Mef
Clinical Research Centre, Hvidovre University Hospital, Copenhagen University, Hvidovre, Denmark.
J Genet Couns. 2011 Jun;20(3):308-13. doi: 10.1007/s10897-011-9349-x. Epub 2011 Jan 26.
Learning about hereditary cancer may influence an individual's self-concept, which otherwise represents a complex but stable cognitive structure. Recently, a 20-statement self-concept scale, with subscales related to stigma-vulnerability and bowel symptom-related anxiety, was developed for Lynch syndrome. We compared the performance of this scale in 591 mutation carriers from Denmark, Sweden and Canada. Principal component analysis identified two sets of linked statements-the first related to feeling different, isolated and labeled, and the second to concern and worry about bowel changes. The scale performed consistently in the three countries. Minor differences were identified, with guilt about passing on a defective gene and feelings of losing one's privacy being more pronounced among Canadians, whereas Danes more often expressed worries about cancer. Validation of the Lynch syndrome self-concept scale supports its basic structure, identifies dependence between the statements in the subscales and demonstrates its applicability in different Western populations.
了解遗传性癌症可能会影响个体的自我概念，否则自我概念代表着一种复杂但稳定的认知结构。最近，针对林奇综合征开发了一种包含20条陈述的自我概念量表，其中分量表与耻辱感易感性和肠道症状相关焦虑有关。我们比较了该量表在来自丹麦、瑞典和加拿大的591名突变携带者中的表现。主成分分析确定了两组相关陈述——第一组与感觉与众不同、孤立和被贴上标签有关，第二组与对肠道变化的担忧有关。该量表在这三个国家的表现一致。发现了一些细微差异，加拿大人对传递缺陷基因的内疚感和失去隐私的感受更为明显，而丹麦人则更常表达对癌症的担忧。林奇综合征自我概念量表的验证支持了其基本结构，确定了分量表中陈述之间的相关性，并证明了其在不同西方人群中的适用性。
