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大麻使用对男性健康的影响。

Impact of cannabis use on male sexual health.

机构信息

Department of Urology, University of Ottawa, Ottawa, Ontario, Canada.

出版信息

J Sex Med. 2011 Apr;8(4):971-5. doi: 10.1111/j.1743-6109.2010.02198.x. Epub 2011 Jan 26.

DOI:10.1111/j.1743-6109.2010.02198.x
PMID:21269404
Abstract

INTRODUCTION

Cannabis (marijuana) is the most widely used illicit drug globally. Given the prevalence of nonprescription illicit drug abuse, there is a growing interest in the study of its potential effects on male sexual health. In this review, we discuss the effects of cannabis on male sexual health.

OBJECTIVE

In this review, we discuss the effects of cannabis on male sexual health. METHODS AND MAIN OUTCOME MEASURE: Critical review of scientific literature examining the impact of cannabis use on male sexual health.

RESULTS

Studies examining the effects of cannabis use on male sexual function have been limited in both quality and quantity. Most results of these studies are conflicting and contradictory. While some did outline the beneficial effects of cannabis in enhancing erectile function, others did not. However, recent animal and in vitro studies have identified potential links between cannabis and sexual health. It appears that cannabis may actually have peripheral antagonizing effects on erectile function by stimulating specific receptors in the cavernous tissue.

CONCLUSIONS

Given the prevalence of cannabis use, and the potential relationships between use and the development of potentially hazardous effects on male sexual function, we encourage renewed use of research resources to determine in-depth mechanistic knowledge, and new clinically oriented studies examining the effect of cannabis on male sexual function.

摘要

简介

大麻( marijuana)是全球使用最广泛的非法药物。鉴于非处方非法药物滥用的普遍性,人们越来越关注大麻对男性性健康的潜在影响。在这篇综述中,我们讨论了大麻对男性性健康的影响。

目的

在这篇综述中,我们讨论了大麻对男性性健康的影响。

方法和主要观察结果

对研究大麻使用对男性性健康影响的科学文献进行批判性回顾。

结果

研究大麻使用对男性性功能影响的研究在质量和数量上都受到限制。这些研究的大多数结果相互矛盾。虽然一些研究概述了大麻在增强勃起功能方面的有益作用,但其他研究并没有。然而,最近的动物和体外研究已经确定了大麻与性健康之间的潜在联系。大麻似乎通过刺激海绵体组织中的特定受体,对勃起功能具有外周拮抗作用。

结论

鉴于大麻的使用普遍性,以及使用与男性性功能潜在危险影响之间的潜在关系,我们鼓励重新利用研究资源,以确定深入的机制知识,并开展新的以临床为导向的研究,以检验大麻对男性性功能的影响。

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J Sex Med. 2011 Apr;8(4):971-5. doi: 10.1111/j.1743-6109.2010.02198.x. Epub 2011 Jan 26.
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