Department of Andrology, Sexology, & STIs, Faculty of Medicine, Cairo University, Cairo 11562, Egypt.
Department of Dermatology, Andrology & STIs, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt.
Sex Med Rev. 2023 Sep 27;11(4):395-411. doi: 10.1093/sxmrev/qead011.
Substance abuse has become a worldwide health problem, leading to numerous consequences such as social problems among family members, abnormal behavior, adverse health effects, and psychological problems as well as economic consequences.
We sought to assess the relationship between substance abuse and male sexual health.
A search was carried out in the following databases: PubMed, MeSH (Medical Subject Headings), Science Direct, Scopus, Cochrane Library, EMBASE, CINAHL, Academic Search Complete, and the Egyptian Knowledge Bank. The following keywords were used to assess the outcomes for relevant associations: illicit drugs, addiction, substance abuse, sexual health, erectile dysfunction, ejaculatory disorders, impotence, orgasm disorders, and sexual performance.
The initial literature search identified a total of 148 articles in all searched databases. After removal of duplicate studies and application of inclusion/exclusion criteria, 75 reported studies were retained for review, including 38 case-control studies and 37 cross-sectional studies. These articles were classified into the following categories according to the type of abused substance addressed: cannabis/marihuana, 16 articles; opioids, 13 articles; heroin, 11 articles; cocaine, 5 articles; tramadol, 6 articles; ketamine, 2 articles; ecstasy, 4 articles; amphetamine, 2 articles; khat, 7 articles; androgen anabolic steroids, 2 articles; and polydrugs, 7 articles. Most of these recruited articles demonstrated a negative impact of the addressed substance on male sexual health, with variable levels.
Substance abuse has negative impacts on male sexual health that should be addressed. More studies conducted with proper methodological and statistical approaches, including logistic regression analysis, are needed to predict the effects of specific substances, considering the rapidly growing effects of non-substance-use disorders on male sexual health.
物质滥用已成为全球性的健康问题，导致许多后果，如家庭成员之间的社会问题、行为异常、健康不良影响和心理问题以及经济后果。
我们旨在评估物质滥用与男性性健康之间的关系。
在以下数据库中进行了搜索：PubMed、MeSH（医学主题词）、Science Direct、Scopus、Cochrane Library、EMBASE、CINAHL、Academic Search Complete 和埃及知识库。使用以下关键词评估相关关联的结果：非法药物、成瘾、物质滥用、性健康、勃起功能障碍、射精障碍、阳痿、性高潮障碍和性表现。
最初的文献搜索在所有搜索数据库中总共确定了 148 篇文章。在去除重复研究并应用纳入/排除标准后，保留了 75 篇报告的研究进行综述，包括 38 项病例对照研究和 37 项横断面研究。这些文章根据所涉及的滥用物质的类型分为以下几类：大麻/大麻，16 篇文章；阿片类药物，13 篇文章；海洛因，11 篇文章；可卡因，5 篇文章；曲马多，6 篇文章；氯胺酮，2 篇文章；摇头丸，4 篇文章；安非他命，2 篇文章；卡特，7 篇文章；雄激素合成类固醇，2 篇文章；和多药物，7 篇文章。大多数这些招募的文章表明所涉及的物质对男性性健康有负面影响，其程度不同。
物质滥用对男性性健康有负面影响，应予以解决。需要更多使用适当的方法学和统计学方法进行的研究，包括逻辑回归分析，以预测特定物质的影响，同时考虑到非物质使用障碍对男性性健康的影响迅速增加。
