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一般性失智量表和一般性失智量表-15 是否充分捕捉到群居老年人的抑郁症状范围?

Do the GDS and the GDS-15 adequately capture the range of depressive symptoms among older residents in congregate housing?

机构信息

Mandel School of Applied Social Sciences, Case Western Reserve University, Cleveland, Ohio, U.S.A.

出版信息

Int Psychogeriatr. 2011 Aug;23(6):950-60. doi: 10.1017/S1041610210002425. Epub 2011 Jan 27.

DOI:10.1017/S1041610210002425
PMID:21269541
Abstract

BACKGROUND

In light of inconsistencies in cut points for identifying non-major depression, this study examined the classification efficiency of the Geriatric Depression Scale (GDS and GDS-15) total scores and individual items, and four additional depressive symptoms for identification of subthreshold, minor, or criterion depression among 166 vulnerable residents of congregate housing.

METHODS

Depression (combined categories of major depressive episode, minor, or subthreshold depression) was determined by the Mini-International Neuropsychiatric Interview (MINI) diagnostic interview depression module administered by telephone to 166 older residents of congregate housing facilities who also completed the 30-item GDS and four other yes/no potential indicators of geriatric depression. Classification agreement and ROC curve analysis for the full and 15-item GDS scale scores were calculated. Individual item hit rates for MINI criterion were calculated for GDS items and four new items.

RESULTS

GDS and GDS-15 at standard cut points had 70-75% agreement with MINI. Best sensitivity and specificity were obtained at lower than standard cut points. Some GDS Withdrawal, Apathy, lack of Vigor (WAV) and cognitive items obtained very low hit rates. New items "I just don't feel like myself" and "I feel I am a burden to others" better discriminated MINI depression than most GDS items and had good item-to-total correlations with the GDS.

CONCLUSIONS

Diagnostic criteria and GDS screen had partial agreement. Some GDS items did not adequately represent depression among functionally impaired or oldest old older adults. Feeling one is a burden and the sense of feeling "different" from usual may be useful indicators of depression among vulnerable older adults.

摘要

背景

鉴于识别非重度抑郁症的切点不一致,本研究在 166 名集中居住的脆弱居民中,检验了老年抑郁量表(GDS 和 GDS-15)总分和单项、以及另外 4 项抑郁症状对亚临床、轻度或标准抑郁的分类效率。

方法

通过电话对集中居住设施中的 166 名老年居民进行的微型国际神经精神访谈(MINI)诊断性访谈抑郁模块,确定抑郁(包括重性抑郁发作、轻度或亚临床抑郁的综合类别)。这些居民还完成了 30 项老年抑郁量表和其他 4 项潜在老年抑郁的是/否指标。计算了全量表和 15 项量表的分类一致性和 ROC 曲线分析。计算了 GDS 项目和 4 项新的项目对 MINI 标准的单项符合率。

结果

GDS 和 GDS-15 标准切点与 MINI 的一致性为 70-75%。低于标准切点时,灵敏度和特异性最佳。GDS 中的某些项目(包括抑郁后淡漠、无活力和认知症状)符合率非常低。新的项目“我只是感觉不像我自己”和“我觉得我是别人的负担”比大多数 GDS 项目更好地区分了 MINI 抑郁,与 GDS 具有良好的项目-总分相关性。

结论

诊断标准和 GDS 筛查有部分一致性。一些 GDS 项目不能充分代表功能受损或最年长的老年人中的抑郁。感觉自己是负担,以及与平时感觉“不同”可能是脆弱老年人抑郁的有用指标。

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