Skerík P, Sechser T, Dolejs Z
Subkatedra dĕtské ORL ILF a ORL odd. FTN, Praha.
Cesk Otolaryngol. 1990 Aug;39(4):185-90.
The authors draw attention to the urgency of antibiotic prophylaxis of early infection in surgical disciplines and emphasize the main principles of its expedient implementation. In otorhinolaryngology antibiotic prophylaxis proves useful in a number of surgical procedures; the authors submit, however, also examples when they do not consider antibiotic prophylaxis expedient. Among antibiotics used for prophylactic administration they consider at present for the majority of ENT operations cephalosporins of the first generation most useful. Their spectrum is roughly equal to the action of penicillin, oxacillin and ampicillin combined. When selecting an antibiotic, however, always ain individual approach must be used and its selection must be adjusted to the epidemiological situation in different areas and health institutions. The prophylactic use of different types of antibiotics cannot have permanent validity, we have to foresee rotation of antibiotics and the introduction of further new preparations.
作者们提请注意外科领域早期感染抗生素预防的紧迫性，并强调其合理实施的主要原则。在耳鼻喉科，抗生素预防在一些外科手术中被证明是有用的；然而，作者们也给出了一些他们认为抗生素预防不合理的例子。在用于预防性给药的抗生素中，他们目前认为第一代头孢菌素对大多数耳鼻喉科手术最为有用。其抗菌谱大致相当于青霉素、苯唑西林和氨苄西林作用的总和。然而，在选择抗生素时，必须始终采用个体化方法，并且其选择必须根据不同地区和医疗机构的流行病学情况进行调整。不同类型抗生素的预防性使用不可能永远有效，我们必须预见抗生素的轮换以及进一步新制剂的引入。
