Bock F, Regenfuss B, Cursiefen C
Augenklinik mit Poliklinik, Labor für Okuläre Angiogenese, Lymphangiogenese und Transplantatimmunologie, Universität Erlangen-Nürnberg, Universitäts-Augenklinik Erlangen, Schwabachanlage 6, 91054, Erlangen, Deutschland.
Ophthalmologe. 2011 Mar;108(3):230-6. doi: 10.1007/s00347-010-2262-0.
There are numerous indications for local antiangiogenic therapy at the ocular surface. These include vision-limiting corneal neovascularization, corneal blood and lymphatic vessels endangering corneal graft survival and tumor-associated lymphangiogenesis. A literature review in PubMed and own clinical and experimental data form the basis for a discussion of the indications, current therapeutic options and potential side-effects of local antiangiogenic therapy at the ocular surface.
眼表局部抗血管生成治疗有多种适应证。这些适应证包括限制视力的角膜新生血管形成、危及角膜移植存活的角膜血管和淋巴管以及肿瘤相关的淋巴管生成。对PubMed的文献综述以及自身的临床和实验数据构成了讨论眼表局部抗血管生成治疗的适应证、当前治疗选择和潜在副作用的基础。
