Department of Pediatrics, Georgia Prevention Institute, Medical College of Georgia, Augusta, GA 30912, USA.
Clin Sci (Lond). 2011 May;120(10):427-40. doi: 10.1042/CS20100385.
Aging is a biological process that affects most cells, organisms and species. Human aging is associated with increased susceptibility to a variety of chronic diseases, including cardiovascular disease, Type 2 diabetes, neurological diseases and cancer. Despite the remarkable progress made during the last two decades, our understanding of the biology of aging remains incomplete. Telomere biology has recently emerged as an important player in the aging and disease process.
衰老是一个影响大多数细胞、生物和物种的生物学过程。人类衰老与多种慢性疾病的易感性增加有关，包括心血管疾病、2 型糖尿病、神经退行性疾病和癌症。尽管在过去的二十年中取得了显著的进展，但我们对衰老生物学的理解仍然不完整。端粒生物学最近成为衰老和疾病过程中的一个重要参与者。
