Department of Endocrinology, Qilu Hospital, Shandong University, Jinan, Shandong, China.
Postgrad Med J. 2011 Apr;87(1026):251-6. doi: 10.1136/pgmj.2010.100453. Epub 2011 Jan 27.
To evaluate the predictive value of the body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) for the presence of several cardiovascular risk conditions-hypertension, dyslipidaemia, metabolic syndrome (MS), and type 2 diabetes-in a Chinese population in Jinan, China.
Data for a representative, cross-sectional sample of 3006 adults (mean age; range 20-74 years) in Jinan from 2007 to 2008 were studied. The association of BMI, WC, and WHtR with cardiovascular risk conditions was assessed by use of receiver operating characteristic curve (ROC) analysis and by calculating the area under the ROC (AUC) and age adjusted odds ratios (ORs) for metabolic syndrome, dyslipidaemia, type 2 diabetes, and hypertension.
AUC cut-off values showed that the association of WHtR and WC was higher than that for BMI for all risk conditions for both sexes, except for hypertension in men. The AUC values for WC showed a higher association with hypertension and metabolic syndrome for women than men (p<0.01 for hypertension, p<0.05 for metabolic syndrome). The ORs were highest for WHtR for metabolic syndrome, diabetes, and hypertension in women. The ORs were highest for BMI for hypertension in men.
Compared with BMI, measures of central obesity, particularly WHtR, show a better association with obesity related cardiovascular risk conditions for both sexes, except for hypertension in men, in Jinan, China.
评估体重指数(BMI)、腰围(WC)和腰高比(WHtR)对中国济南市人群多种心血管风险状况(高血压、血脂异常、代谢综合征(MS)和 2 型糖尿病)存在的预测价值。
对 2007 年至 2008 年济南市 3006 名成年人(平均年龄;范围 20-74 岁)的代表性横断面样本进行研究。使用受试者工作特征曲线(ROC)分析和计算代谢综合征、血脂异常、2 型糖尿病和高血压的 ROC 下面积(AUC)和年龄校正比值比(OR),评估 BMI、WC 和 WHtR 与心血管风险状况的相关性。
AUC 截断值表明,除男性高血压外,WHtR 和 WC 与所有性别风险状况的相关性均高于 BMI。对于女性,WC 的 AUC 值与高血压和代谢综合征的相关性高于男性(高血压 p<0.01,代谢综合征 p<0.05)。对于女性,WHtR 与代谢综合征、糖尿病和高血压的 OR 最高。对于男性,BMI 与高血压的 OR 最高。
与 BMI 相比,中心性肥胖的衡量标准,特别是 WHtR,与中国济南市男女两性的肥胖相关心血管风险状况的相关性更好,除男性高血压外。