National Electronics and Computer Technology Center, Pathumthani, Thailand.
Anal Chim Acta. 2011 Feb 21;687(2):114-28. doi: 10.1016/j.aca.2010.12.022. Epub 2010 Dec 21.
Monolithic multichannel quartz crystal microbalance (MQCM) is an emerging technology for advanced sensing and measurement applications. In this report, a comprehensive review of MQCM technology is presented. Firstly, basic MQCM's design, simulation and characterization with emphasis on acoustic interference are described. Next, various MQCM schemes to minimize interference and enhance sensitivity of conventional MQCM devices based on modification of quartz substrate structure are digested. These include mesa, convex and x-axis inversion structures. Three important MQCM sensing platforms and their application areas are then discussed. These comprise MQCM as a static multichannel detector, series MQCM as a multichannel detector for the flow injection analysis and multi-frequency QCM for multi-sensitivity/multi-dynamic range detection. Finally, potential MQCM applications including electronic noses, bio-sensor arrays, and photocatatalytic measurement are illustrated and prospective MQCM applications including electronic tongues and electrochemical measurement are suggested.
整体式多通道石英晶体微天平 (MQCM) 是一种新兴的高级传感和测量应用技术。本报告对 MQCM 技术进行了全面综述。首先,描述了基本 MQCM 的设计、模拟和特性,重点是声学干扰。接下来,消化了各种基于石英衬底结构修改来最小化干扰并提高传统 MQCM 器件灵敏度的 MQCM 方案,包括台面、凸面和 x 轴反转结构。然后讨论了三个重要的 MQCM 传感平台及其应用领域。这些包括 MQCM 作为静态多通道检测器、用于流动注射分析的串联 MQCM 以及用于多灵敏度/多动态范围检测的多频 QCM。最后,说明了 MQCM 的潜在应用,包括电子鼻、生物传感器阵列和光催化测量,并提出了包括电子舌和电化学测量在内的潜在 MQCM 应用。