Department of Orthopaedics, University of Rochester, 601 Elmwood Ave, Box 665, Rochester, NY 14534, USA.
Clin Orthop Relat Res. 2011 Aug;469(8):2225-36. doi: 10.1007/s11999-011-1779-0.
Patients with impaired bone quality who suffer a fragility fracture face substantial challenges in both their short- and long-term care. In addition to poor bone quality, many of these patients have multiple medical comorbidities that alter their surgical risk and affect their ultimate functional recovery. Some medical issues can contribute to the altered bone quality and must be addressed to prevent future fractures.
QUESTIONS/PURPOSES: This review summarizes the modifications in perioperative management and fracture fixation in patients with common fragility fractures who have impaired bone quality. It also summarizes the postoperative diagnosis and treatment of secondary causes of impaired bone quality in these patients.
We performed a PubMed search, and literature published after 2000 was prioritized, with the exception of benchmark clinical trial studies published before 2000.
Patients with altered bone quality require rapid perioperative management of multiple medical comorbidities. Implant selection in patients with poor quality bone should permit early weightbearing, and constructs should maximize surface area contact with the remaining bone. Long-term diagnosis and treatment of other disease states contributing to poor bone quality (vitamin D deficiency/insufficiency, hypothyroidism, hyperthyroidism, hyperparathyroidism, Cushing's disease, and hypogonadism) must occur to minimize the chances of future fractures.
Recognition of patients with impaired bone quality and proper treatment of their special needs in both the short and long term are essential for their best opportunity for maximal functional recovery and prevention of future fractures.
患有骨质量受损并发生脆性骨折的患者,在短期和长期护理方面都面临着巨大的挑战。除了骨质量差之外,这些患者中的许多人还患有多种合并症,这会改变他们的手术风险,并影响他们最终的功能恢复。一些医疗问题会导致骨质量改变,必须加以解决以防止未来发生骨折。
问题/目的:本文总结了骨质量受损的常见脆性骨折患者围手术期管理和骨折固定方式的改变,还总结了这些患者术后继发骨质量受损的诊断和治疗。
我们进行了 PubMed 检索,优先选择 2000 年后发表的文献,但 2000 年前发表的具有里程碑意义的临床试验研究除外。
骨质量改变的患者需要快速处理多种合并症。在骨质量差的患者中,应选择允许早期负重的植入物,且固定装置应使与剩余骨的表面积接触最大化。还必须长期诊断和治疗导致骨质量差的其他疾病状态(维生素 D 缺乏/不足、甲状腺功能减退、甲状腺功能亢进、甲状旁腺功能亢进、库欣病和性腺功能减退),以最大限度地降低未来发生骨折的几率。
认识到骨质量受损的患者,并在短期和长期内对他们的特殊需求进行适当的治疗,对于他们获得最佳的最大功能恢复机会和预防未来骨折至关重要。