Mullinger Karen, Bowtell Richard
School of Physics and Astronomy, Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, UK.
Methods Mol Biol. 2011;711:303-26. doi: 10.1007/978-1-61737-992-5_15.
The combination of electroencephalography (EEG) with functional magnetic resonance imaging (fMRI) forms a powerful tool for the investigation of brain function, but concurrent implementation of EEG and fMRI poses many technical challenges. Here, the motivation for combining EEG and fMRI is explored and methods underlying the combination are described. After a brief introduction to the two different techniques, the advantages and disadvantages of different methods of data recording are detailed, followed by a description of the artefacts encountered when performing EEG and fMRI measurements simultaneously, and the methods which have been developed to eliminate these artefacts. Important safety considerations and potential pitfalls associated with simultaneous recording are also described. The ways in which EEG and fMRI data analysis can be integrated are then described along with examples of key work which illustrate the power of combined EEG/fMRI measurements. The chapter concludes with a brief discussion of future directions for combined EEG/fMRI research.
脑电图（EEG）与功能磁共振成像（fMRI）相结合，形成了一种用于研究脑功能的强大工具，但同时实施EEG和fMRI带来了许多技术挑战。本文探讨了将EEG与fMRI相结合的动机，并描述了这种结合所基于的方法。在简要介绍这两种不同技术之后，详细阐述了不同数据记录方法的优缺点，接着描述了同时进行EEG和fMRI测量时遇到的伪迹，以及为消除这些伪迹而开发的方法。还介绍了与同步记录相关的重要安全注意事项和潜在陷阱。然后描述了EEG和fMRI数据分析可以整合的方式，并列举了关键研究工作的示例，以说明EEG/fMRI联合测量的强大功能。本章最后简要讨论了EEG/fMRI联合研究的未来方向。
