Buchner A, Merrell P W, Leider A S, Hansen L S
Department of Oral Pathology and Oral Medicine, School of Dental Medicine, Tel Aviv University, Israel.
Int J Oral Maxillofac Surg. 1990 Dec;19(6):337-40. doi: 10.1016/s0901-5027(05)80076-1.
Oral focal mucinosis (OFM) is an uncommon clinicopathological entity which is considered to be the oral counterpart of cutaneous focal mucinosis and/or cutaneous myxoid cyst. It is comprised of a clinically elevated mass with a histological picture of localized areas of myxomatous connective tissue. The present study adds 15 new cases of OFM to the literature and analyzes their clinical, histological and histochemical features. Most of the lesions were located in the gingiva and alveolar mucosa. The nature of the lesion is unclear and it is suggested that the mucinous accumulation is the result of fibroblastic overproduction of hyaluronic acid.
口腔局灶性黏液瘤（OFM）是一种罕见的临床病理实体，被认为是皮肤局灶性黏液瘤和/或皮肤黏液样囊肿的口腔对应物。它由临床上隆起的肿块组成，组织学表现为黏液瘤样结缔组织的局部区域。本研究为文献增添了15例新的口腔局灶性黏液瘤病例，并分析了它们的临床、组织学和组织化学特征。大多数病变位于牙龈和牙槽黏膜。病变的性质尚不清楚，有人认为黏液积聚是成纤维细胞过度产生透明质酸的结果。
