Bharti Vipin, Singh Jagmohan
Department, of Periodontology, Government Dental College and Hospital, Patiala, Punjab, India.
Contemp Clin Dent. 2012 Sep;3(Suppl 2):S214-8. doi: 10.4103/0976-237X.101098.
Oral focal mucinosis (OFM), an oral counterpart of cutaneous focal mucinosis, is a rare disease of unknown etiology. Its pathogenesis may be due to the overproduction of hyaluronic acid by a fibroblast, at the expense of collagen production, resulting in focal myxoid degeneration of the connective tissue, primarily affecting the mucosa overlying the bone. It has no distinctive clinical features, as the diagnosis is solely based on the histopathological features. This article reports of a 32-year-old female having the rare disease of oral focal mucinosis, involving the posterior palatal mucosa, and discusses its clinicopathological features and differential diagnosis of myxomatous lesions of the oral cavity.
口腔局灶性黏液病（OFM）是皮肤局灶性黏液病的口腔对应疾病，是一种病因不明的罕见疾病。其发病机制可能是成纤维细胞过度产生透明质酸，而以胶原蛋白产生为代价，导致结缔组织局灶性黏液样变性，主要影响覆盖骨的黏膜。它没有独特的临床特征，因为诊断完全基于组织病理学特征。本文报道了一名32岁女性患有罕见的口腔局灶性黏液病，累及腭后黏膜，并讨论了其临床病理特征及口腔黏液瘤样病变的鉴别诊断。
