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口腔局灶性黏液瘤病:1例罕见病例并文献复习

Oral focal mucinosis: a rare case with literature review.

作者信息

Sowmya G V, Manjunatha Bhari Sharanesha, Nahar Prashant, Aggarwal Hersheal

机构信息

Department of Oral Medicine & Radiology, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India.

Department of Dental Anatomy & Oral Biology, Faculty of Dentistry, University of Taif, Taif, Saudi Arabia.

出版信息

BMJ Case Rep. 2015 Mar 10;2015:bcr2014208321. doi: 10.1136/bcr-2014-208321.

Abstract

Oral focal mucinosis (OFM) is an unusual disease that affects diverse localised areas of the mouth, where the connective tissue undergoes focal degeneration. It was described for the first time by Tomich in 1974. It presents as an asymptomatic pedunculated or sessile growth, commonly on the gingiva, with most cases being in women. Its pathogenesis is linked to overproduction of hyaluronic acid by fibroblasts during collagen production, ensuing in focal myxoid degeneration. It has no characteristic features and diagnosis depends on histological scrutiny. We report a rare case of oral focal mucinosis affecting a 54-year-old man who presented with a sessile gingival growth mimicking a common tumour-like lesion.

摘要

口腔局灶性黏液瘤(OFM)是一种罕见疾病,可累及口腔的不同局部区域,此处结缔组织会发生局灶性变性。1974年,托米奇首次对其进行了描述。它表现为无症状的带蒂或无蒂肿物,常见于牙龈,多数病例发生在女性身上。其发病机制与成纤维细胞在胶原蛋白生成过程中过度产生透明质酸有关,进而导致局灶性黏液样变性。它没有特征性表现,诊断依赖于组织学检查。我们报告了一例罕见的口腔局灶性黏液瘤病例,患者为一名54岁男性,表现为无蒂牙龈肿物,酷似常见的肿瘤样病变。

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Oral focal mucinosis.口腔局灶性黏液瘤病
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