Ena Sharma, Ramesh Alampalli
Department of Pediodontics, Oxford Dental College and Hospital, Bangalore, India.
Ethiop J Health Sci. 2013 Jul;23(2):178-82.
Oral focal mucinosis (OFM) is a rare soft tissue lesion of unknown etiology. Clinically, it is most commonly found on the gingiva and presents as a painless, sessile or pedunculated mass of the same colour as the surrounding mucosa. Histologically, it is characterized by focal myxoid degeneration of connective tissue. OFM occurs predominantly in adults during the fourth and fifth decade of life, although it has been reported infrequently in children and adolescents. Its diagnosis mainly relies on histological analysis and the treatment involves complete surgical excision. Its recurrence is unreported. The aim of this report of two cases is to describe the clinical and histological presentation and subsequent management of OFM. The cause of OFM remains unknown. The cases presented in this report bring OFM to the attention of anatomical pathologists while considering the differential diagnosis of myxoid lesions of the oral cavity.
口腔局灶性黏液瘤（OFM）是一种病因不明的罕见软组织病变。临床上，它最常见于牙龈，表现为与周围黏膜颜色相同的无痛性、无蒂或有蒂肿块。组织学上，其特征为结缔组织的局灶性黏液样变性。OFM主要发生于40至50岁的成年人，不过儿童和青少年中也有罕见报道。其诊断主要依靠组织学分析，治疗方法为完整手术切除。目前尚无复发的报道。本报告两例病例的目的是描述OFM的临床和组织学表现以及后续处理。OFM的病因仍然不明。本报告中的病例在考虑口腔黏液样病变的鉴别诊断时，引起了解剖病理学家对OFM的关注。
