Can Fam Physician. 1983 Feb;29:291-3.
Resistant hypertension is a common and serious problem. Before major changes in management are undertaken, seven questions should be asked: 1. What is a realistic goal blood pressure? 2. Is the erect blood pressure below the goal? 3. Is the patient compliant? 4. Does the patient have `office hypertension'? 5. Is the patient using medication which aggravates hypertension? 6. Are there confounding renal or cardiovascular responses to medication? 7. Has a secondary cause of hypertension been overlooked? Newer and more potent medications such as captopril and minoxidil should be recommended only after exploration of these questions and after careful clinical and laboratory evaluation.
耐药性高血压是一个常见且严重的问题。在进行重大管理改变之前，应提出以下七个问题：1. 实际的目标血压是多少？2. 立位血压是否低于目标？3. 患者是否依从？4. 患者是否患有“诊室高血压”？5. 患者是否使用加重高血压的药物？6. 药物治疗是否存在影响肾脏或心血管的不良反应？7. 是否忽略了高血压的继发原因？只有在探讨了这些问题并进行了仔细的临床和实验室评估后，才能推荐使用新型且强效的药物，如卡托普利和米诺地尔。
