Division of Urology, Federal University of São Paulo, São Paulo, Brazil.
Neurourol Urodyn. 2011 Apr;30(4):515-9. doi: 10.1002/nau.21008. Epub 2011 Jan 31.
The aims of this study were to investigate quality of life (QoL) due to physical and psychological changes occurring in elderly men and to identify associated factors between lower urinary tract symptoms (LUTS) and aging male symptoms (ADAM).
This was a case-control study whereby 200 elderly men were recruited from the community and the Urology and Geriatrics ambulatories. Subjects were asked to fill out the Aging Male Symptoms Scale (AMS), World Health Organization Quality of Life-BREF and -OLD, and IPSS questionnaires. Participants were classified in two groups according to IPSS: group I (moderate to severe symptoms) and group II (mild symptoms).
The AMS scale and both QoL questionnaires of group I showed significantly worse median scores in all parameters. The average somatic and sexual subscore was significantly higher in group I (P < 0.0005). The social and environmental domains presented the most significant differences (P < 0.0005) in both questionnaires, and the mean of the WHOQOL-OLD score was significantly lower in group I (P < 0.0005).
Moderate to severe ADAM and LUTS impact significantly all parameters of HRQOL and generic QoL proposed by the WHO. There was correlation between severity of LUTS and severity of the following ADAM: depression, feeling burnt out, decline of feeling of general well-being, joint and body complaints, insomnia, weakness of muscles, feeling that the peak had passed, decrease of sexual performance, and decrease of morning erections.
本研究旨在探讨老年男性因身体和心理变化而导致的生活质量(QoL)问题,并确定下尿路症状(LUTS)与衰老男性症状(ADAM)之间的相关因素。
这是一项病例对照研究,共招募了 200 名来自社区和泌尿科及老年病门诊的老年男性。要求受试者填写衰老男性症状量表(AMS)、世界卫生组织生活质量简表-BREF 和 -OLD 以及 IPSS 问卷。根据 IPSS 将参与者分为两组:组 I(中重度症状)和组 II(轻度症状)。
组 I 的 AMS 量表和两个 QoL 问卷的中位数评分在所有参数上均显著较差。组 I 的平均躯体和性功能亚评分明显更高(P<0.0005)。社会和环境领域在两个问卷中均呈现出最显著的差异(P<0.0005),且组 I 的 WHOQOL-OLD 评分均值明显较低(P<0.0005)。
中重度 ADAM 和 LUTS 显著影响 WHO 提出的所有 HRQoL 和一般 QoL 参数。LUTS 的严重程度与以下 ADAM 的严重程度之间存在相关性:抑郁、疲惫感、整体幸福感下降、关节和身体不适、失眠、肌肉无力、感觉巅峰已过、性功能下降和晨勃减少。