Devane Liam A, Evers Judith, Jones James F X, Ronan O'Connell P
School of Medicine and Medical Sciences, University College Dublin, Belfield, Dublin 4, Ireland.
School of Medicine and Medical Sciences, University College Dublin, Belfield, Dublin 4, Ireland; Centre for Colorectal Disease, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
Surgeon. 2015 Jun;13(3):156-62. doi: 10.1016/j.surge.2014.11.002. Epub 2015 Jan 23.
Sacral nerve stimulation (SNS) was originally developed in the field of urinary incontinence. Without adaptation, it was subsequently applied to treat faecal incontinence. SNS has now become a first line therapy for this socially disabling condition, however the mechanism of action is unknown. This review examines the evidence for stimulation parameters currently used for SNS in humans and considers the potential electrophysiological effects of changing these parameters. However, without a proper understanding of the physiology of SNS, changing stimulation parameters remains empirical.
骶神经刺激（SNS）最初是在尿失禁领域开发的。未经调整，它随后被应用于治疗大便失禁。SNS现已成为这种具有社会致残性疾病的一线治疗方法，但其作用机制尚不清楚。这篇综述考察了目前用于人体SNS的刺激参数的证据，并考虑了改变这些参数可能产生的电生理效应。然而，由于对SNS的生理学缺乏恰当的理解，改变刺激参数仍然是凭经验的。
