Department of Physiology, Development, and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK.
Cell Metab. 2011 Feb 2;13(2):115-7. doi: 10.1016/j.cmet.2011.01.011.
Maternal nutrition and metabolism are critical determinants of adult offspring health. Recent reports describe adverse offspring outcomes associated with the father's diet, indicating nongenetic inheritance of paternal experience. Determining underlying mechanisms may require reconsideration of our understanding of the heritability of epigenetic states.
母体营养和代谢是成年后代健康的关键决定因素。最近的报告描述了与父亲饮食相关的不良后代结果，表明了父亲经验的非遗传继承。确定潜在机制可能需要重新考虑我们对表观遗传状态遗传性的理解。
