Arnold W, Huth F
Virchows Arch A Pathol Anat Histol. 1978 Oct 3;379(4):285-98. doi: 10.1007/BF00464472.
Light and electron microscopic investigations of four cases of juvenile nasopharyngeal fibroma revealed characteristic structures; a fibrous stroma, an inclination to hyalinisation and formation of scar like tissue, a lacunar thin walled vascular component, large numbers of mast cells and of fibroblasts. The tumor fibroblasts contained different nuclear bodies and particles. There existed five different types of more or less complex spherical bodies. The previously described nuclear electron dense particles with an electron lucent halo could be divided into four groups measuring 60, 90, 150, and 300 nm in diameter. In addition to the previously described ultrastructural properties of the tumors, the nuclei of the tumor fibroblasts were found to contain virus like particles. These particles were less electron dense, measuring 40 to 55 nm in diameter and arranged in groups throughout the nucleoplasm; they were different from chromatin condensations and from perichromatin granules. The structure and the size of the smallest particles was not comparable with the other nuclear inclusions.
对4例青少年鼻咽纤维瘤进行光镜和电镜研究，发现了其特征性结构：纤维性基质、易于玻璃样变和形成瘢痕样组织、腔隙性薄壁血管成分、大量肥大细胞和成纤维细胞。肿瘤成纤维细胞含有不同的核体和颗粒。存在五种不同类型的或多或少复杂的球形体。先前描述的具有电子透明晕的核电子致密颗粒可分为四组，直径分别为60、90、150和300nm。除了先前描述的肿瘤超微结构特征外，还发现肿瘤成纤维细胞核内含有病毒样颗粒。这些颗粒电子密度较低，直径为40至55nm，成群分布于整个核质中；它们与染色质凝聚物和核周染色质颗粒不同。最小颗粒的结构和大小与其他核内包涵体不可比。
