Stiller D, Katenkamp D, Küttner K
Virchows Arch A Pathol Anat Histol. 1976 Sep 21;371(3):273-82. doi: 10.1007/BF00433074.
An electron-microscopic study of 9 nasopharyngeal angiofibromas was performed in order to elucidate the ultrastructural characteristics. Stromal fibroblasts and proliferating cells of the microvasculature were found. The stromal fibroblasts were subdivided into 3 different groups: (1) "classical" fibroblasts, (2) fibroblasts with histiocytelike features, and (3) fibroblasts with myoid features. By proliferation the cells of the capillary vessels change into stromal cells. A particular pattern of nuclei and dense intranuclear granules is only found in stromal fibroblasts. Consequently fibroblasts as well as cells of the microvasculature contribute to the pool of tumor cells.
为阐明超微结构特征，对9例鼻咽血管纤维瘤进行了电子显微镜研究。发现了基质成纤维细胞和微血管的增殖细胞。基质成纤维细胞可分为3种不同类型：（1）“经典”成纤维细胞，（2）具有组织细胞样特征的成纤维细胞，（3）具有肌样特征的成纤维细胞。通过增殖，毛细血管的细胞转变为基质细胞。仅在基质成纤维细胞中发现了一种特殊的核模式和致密的核内颗粒。因此，成纤维细胞以及微血管的细胞都对肿瘤细胞池有贡献。
