Can Fam Physician. 1982 Oct;28:1829-32.
Although similar cases have been reported as far back as 1927, the term toxic shock syndrome was coined in 1978 to describe an acute fever involving Staph. aureus. The reported mortality rate in Canada is 3.8%, but may be much higher. Association with tampon use was made in 1980, but is still unclear. Treatment remains supportive and is aimed at reducing risk of recurrence, until the role of the exotoxin can be explained. This article reviews reported cases to date, listing diagnostic criteria, signs and symptoms. A high index of suspicion for this new syndrome is recommended.
尽管早在 1927 年就有类似的病例报告,但直到 1978 年才出现“中毒性休克综合征”这一术语来描述一种涉及金黄色葡萄球菌的急性发热。据报道,加拿大的死亡率为 3.8%,但可能更高。1980 年发现与使用卫生棉条有关,但仍不清楚。治疗方法仍然是支持性的,目的是降低复发的风险,直到能够解释外毒素的作用。本文回顾了迄今为止报告的病例,列出了诊断标准、体征和症状。建议对这种新综合征保持高度警惕。