Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117576.
Chem Commun (Camb). 2011 Mar 21;47(11):3284-6. doi: 10.1039/c0cc04706f. Epub 2011 Feb 1.
A novel tandem-biocatalysts system consisting of a monooxygenase-containing microorganism and an alcohol dehydrogenase is developed for the concurrent oxidations of methylene groups to ketones in one pot, providing green, clean and simple access to valuable ketones with high yield, excellent selectivity and efficient cofactor recycling.
开发了一种新型串联生物催化剂体系，由含有单加氧酶的微生物和醇脱氢酶组成，可将亚甲基同时氧化为酮，一锅法提供了绿色、清洁和简单的方法，以高产率、优异的选择性和有效的辅因子循环获得有价值的酮。
