Department of Trauma, Hand and Reconstructive Surgery, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Int Orthop. 2011 Nov;35(11):1695-701. doi: 10.1007/s00264-010-1199-x. Epub 2011 Feb 1.
Internal fixation is a therapeutic mainstay for treatment of undisplaced femoral neck fractures and fractures without posterior comminution. The best treatment for unstable and comminuted fractures, however, remains controversial, especially in older patients. The present study was designed to assess the utility of the Intertan Nail® (IT) for stabilization of comminuted Pauwels type III fractures compared to dynamic hips screw (DHS).
Randomized on the basis of bone mineral density, 32 human femurs were assigned to four groups. Pauwels type III fractures were osteomized with a custom-made saw guide. In 16 specimens the posteromedial support was removed and all femurs were instrumented with an IT or a DHS. All constructs were tested with nondestructive axial loading to 700N, cyclical compression to 1,400N (10,000 cycles), and loading to failure. Outcome measures included number of survived cycles, mechanical stiffness, head displacement and load to failure.
Postoperative mechanical stiffness and stiffness after cyclical loading were significantly reduced in all constructs regardless of the presence of a comminution defect (p = 0.02). Specimens stabilized with the IT had a lower construct displacement (IT, 8.5 ± 0.5 mm vs. DHS, 14.5 ± 2.2 mm; p = 0.007) and sustained higher failure loads (IT, 4929 ± 419 N vs. DHS, 3505 ± 453 N; p = 0.036) than the DHS constructs.
In comminuted Pauwels type III fractures, the fixation with the IT provided sufficient postoperative mechanical strength, comparable rate of femoral head displacement, and a similar tolerance of physiological loads compared to fractures without comminution. The absence of the posteromedial support in comminuted fractures tended to reduce the failure load regardless of the fixation method.
内固定是治疗无移位股骨颈骨折和无后粉碎骨折的主要治疗方法。然而,对于不稳定和粉碎性骨折,最佳治疗方法仍存在争议,尤其是在老年患者中。本研究旨在评估 Intertan Nail®(IT)固定治疗不稳定型、粉碎性 Pauwels Ⅲ型骨折的效果,与动力髋螺钉(DHS)相比。
根据骨密度随机分组,32 个人体股骨分为四组。用定制的锯导板将 Pauwels Ⅲ型骨折切开。16 个标本去除后内侧支撑,所有股骨均用 IT 或 DHS 进行器械固定。所有构建体均进行非破坏性轴向加载至 700N、循环压缩至 1400N(10000 次循环)和加载至失效。观察指标包括存活循环次数、力学刚度、股骨头位移和失效载荷。
所有构建体的术后力学刚度和循环加载后的刚度均显著降低,无论是否存在粉碎性缺陷(p = 0.02)。用 IT 固定的标本具有较低的构建体位移(IT,8.5 ± 0.5mm 比 DHS,14.5 ± 2.2mm;p = 0.007)和更高的失效载荷(IT,4929 ± 419N 比 DHS,3505 ± 453N;p = 0.036),比 DHS 构建体更高。
在粉碎性 Pauwels Ⅲ型骨折中,IT 固定提供了足够的术后力学强度,与无粉碎性骨折相比,股骨头位移率相当,对生理负荷的耐受性相似。粉碎性骨折中后内侧支撑的缺失,无论固定方法如何,都会降低失效载荷。