Zhdanova V M, Al'tshteĭn A D
Vopr Onkol. 1978;24(9):8-15.
The modern concepts of tumorigenic virus oncogenes are discussed. The available literature data on the identification of oncogenes of polyoma-, adeno- and oncoviruses and the corresponding protein the products of oncogenes, are reported. Under consideration is the idea of the cellular origin of virus oncogenes. It is suggested that the study of virus oncogenes would offer some new methodical approaches to the identification of cell genes, which impairment results in cell malignification.
本文讨论了致瘤病毒癌基因的现代概念。报告了有关多瘤病毒、腺病毒和肿瘤病毒癌基因的鉴定以及癌基因相应蛋白质产物的现有文献数据。文中考虑了病毒癌基因细胞起源的观点。有人提出，对病毒癌基因的研究将为鉴定细胞基因提供一些新的方法学途径，这些基因的损伤会导致细胞恶性转化。
