Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.
J Am Chem Soc. 2011 Mar 2;133(8):2556-66. doi: 10.1021/ja108028m. Epub 2011 Feb 4.
Mercury is a major threat to the environment and to human health. It is highly desirable to develop a user-friendly kit for on-site mercury detection. Such a method must be able to detect mercury below the threshold levels for drinking water, 1-2 ppb. We developed a fluorescence method based on the oxymercuration of vinyl ethers to detect mercury in dental and environmental samples. Chloride ions interfered with the oxymercuration reaction, but the addition of AgNO(3) solved this problem. Fine electronic and structural tuning led to the development of a more responsive probe that was less sensitive to chloride ion interference. This second-generation probe could detect 1 ppb mercury ions in water.
汞是对环境和人类健康的主要威胁。非常需要开发一种用于现场汞检测的用户友好型试剂盒。这种方法必须能够检测饮用水中低于阈值水平的汞,即 1-2 ppb。我们开发了一种基于乙烯基醚的氧汞化作用的荧光法来检测牙科和环境样品中的汞。氯离子会干扰氧汞化反应,但加入 AgNO3可以解决这个问题。精细的电子和结构调谐导致开发出一种对氯离子干扰不敏感的响应性更强的探针。这种第二代探针可以在水中检测到 1 ppb 的汞离子。