Clarke B S, Mannion P A, White R A S
Dick White Referrals, Station Farm, London Road, Newmarket CB8 0UH.
J Small Anim Pract. 2011 Mar;52(3):163-7. doi: 10.1111/j.1748-5827.2011.01019.x. Epub 2011 Feb 5.
Metastatic spread to the ribs in a 15-year-old, male, neutered, Irish setter is reported occurring secondary to an oral squamous cell carcinoma (SCC). The dog presented with a history of a rapidly growing SCC of the right upper incisive region, which was confirmed by histopathology as a SCC. Thoracic radiographs showed bony lesions associated with the body of the right third rib, and the fifth and seventh costal cartilages. A rostral partial maxillectomy was performed as palliative treatment for the oral mass and a core biopsy of the lesion on the third rib was performed. The rib lesion was identified histopathologically as a metastatic SCC. A review of the literature of oropharyngeal SCC and the metastatic potential of non-tonsillar SCC is presented, in particular metastatic bone disease. This case report suggests possible implications of metastatic bone disease for treatment and prognosis for future cases of non-tonsillar SCC.
据报道，一只15岁已绝育的雄性爱尔兰赛特犬因口腔鳞状细胞癌（SCC）继发肋骨转移。该犬有右上切齿区域快速生长的SCC病史，经组织病理学确诊为SCC。胸部X光片显示右侧第三肋骨体、第五和第七肋软骨有骨质病变。对口腔肿物进行了姑息性治疗，即实施了上颌前部切除术，并对第三肋骨的病变进行了核心活检。肋骨病变经组织病理学鉴定为转移性SCC。本文综述了口咽SCC的文献以及非扁桃体SCC的转移潜能，特别是转移性骨病。本病例报告提示转移性骨病对未来非扁桃体SCC病例的治疗和预后可能产生的影响。
