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体外循环(CPB)对恶性疾病的有害影响。

Detrimental effect of cardiopulmonary bypass (CPB) on malignant disease.

作者信息

Darwazah Ahmad K, Shehata Saleh

机构信息

Department of Cardiac Surgery, Makassed Hospital, Jerusalem, Israel.

出版信息

J Cardiothorac Surg. 2011 Feb 4;6:13. doi: 10.1186/1749-8090-6-13.

Abstract

Patients with coronary artery disease associated with malignancy are a difficult group of patients to treat. The ideal approach to manage them is still controversial. Both problems can be manage by either a combined or staged operation. The use of CPB during revascularization of the myocardium among patients with malignant disease, may have an effect on dissimination of malignant cells. This was observed among two of our patients. We believe that the use of off-pump technique to revascularize the myocardium is a safe approach and can be performed either in combined or staged surgery to resect malignant disease.

摘要

患有与恶性肿瘤相关的冠状动脉疾病的患者是一类难以治疗的患者群体。管理他们的理想方法仍存在争议。这两个问题都可以通过联合手术或分期手术来处理。在患有恶性疾病的患者进行心肌血运重建期间使用体外循环,可能会对恶性细胞的播散产生影响。我们的两名患者就出现了这种情况。我们认为,使用非体外循环技术进行心肌血运重建是一种安全的方法,可在联合手术或分期手术中用于切除恶性疾病。

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本文引用的文献

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Combined operation for lung cancer and cardiac disease.
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Immunological aspects of cardiopulmonary bypass.体外循环的免疫学方面。
J Cardiothorac Anesth. 1990 Apr;4(2):245-58. doi: 10.1016/0888-6296(90)90246-c.

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