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印度尼西亚的疟疾分布、流行情况、耐药性和控制情况。

Malaria distribution, prevalence, drug resistance and control in Indonesia.

机构信息

Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia.

出版信息

Adv Parasitol. 2011;74:41-175. doi: 10.1016/B978-0-12-385897-9.00002-1.

Abstract

Approximately 230 million people live in Indonesia. The country is also home to over 20 anopheline vectors of malaria which transmit all four of the species of Plasmodium that routinely infect humans. A complex mosaic of risk of infection across this 5000-km-long archipelago of thousands of islands and distinctive habitats seriously challenges efforts to control malaria. Social, economic and political dimensions contribute to these complexities. This chapter examines malaria and its control in Indonesia, from the earliest efforts by malariologists of the colonial Netherlands East Indies, through the Global Malaria Eradication Campaign of the 1950s, the tumult following the coup d'état of 1965, the global resurgence of malaria through the 1980s and 1990s and finally through to the decentralization of government authority following the fall of the authoritarian Soeharto regime in 1998. We detail important methods of control and their impact in the context of the political systems that supported them. We examine prospects for malaria control in contemporary decentralized and democratized Indonesia with multidrug-resistant malaria and greatly diminished capacities for integrated malaria control management programs.

摘要

印度尼西亚约有 2.3 亿人口。这个国家也是超过 20 种疟蚊的栖息地,疟蚊传播所有四种经常感染人类的疟原虫。在这个由数千个岛屿和独特生境组成的 5000 公里长的群岛上,感染风险呈现出复杂的马赛克状,严重挑战了疟疾控制工作。社会、经济和政治等方面都加剧了这种复杂性。本章探讨了印度尼西亚的疟疾及其控制情况,从殖民时期荷兰东印度群岛的疟疾学家最早的努力开始,到 20 世纪 50 年代的全球疟疾根除运动,再到 1965 年政变后的动荡时期,再到 20 世纪 80 年代和 90 年代全球疟疾的再次爆发,最后是 1998 年独裁的苏哈托政权倒台后政府权力的下放。我们详细介绍了在支持它们的政治体系背景下,重要的控制方法及其影响。我们考察了在疟疾耐药性和综合疟疾控制管理计划能力大大减弱的情况下,当代权力下放和民主化的印度尼西亚控制疟疾的前景。

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