Bienzle Dorothee, Vernau William
Department of Pathobiology, University of Guelph, Ontario, Canada.
Clin Lab Med. 2011 Mar;31(1):21-39. doi: 10.1016/j.cll.2010.10.001.
Lymphoma in dogs is a heterogeneous cancer with highly variable prognosis. Many types of canine lymphoma have similar counterparts in the World Health Organization classification of human lymphoid tumors. The most common variant of canine lymphoma is diffuse large B-cell lymphoma, which, if treated with multiagent chemotherapy, has a survival time of approximately 12 months. T-cell lymphomas are more heterogeneous and high- and low-grade variants are common, which necessitates classification beyond B- versus T-cell lineage.
犬淋巴瘤是一种异质性癌症,预后差异很大。许多类型的犬淋巴瘤在世界卫生组织人类淋巴肿瘤分类中有相似的对应类型。犬淋巴瘤最常见的变体是弥漫性大B细胞淋巴瘤,如果采用多药化疗,其生存时间约为12个月。T细胞淋巴瘤更为异质,高分级和低分级变体都很常见,这就需要在B细胞与T细胞谱系之外进行分类。