Genetic and molecular basis of inflammasome-mediated disease.
作者信息
Hoffman Hal M, Brydges Susannah D
机构信息
Department of Pediatrics, University of California at San Diego, La Jolla, California 92093, USA.
出版信息
J Biol Chem. 2011 Apr 1;286(13):10889-96. doi: 10.1074/jbc.R110.135491. Epub 2011 Feb 4.
Abstract
摘要
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本文引用的文献
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Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase.烟曲霉通过需要 ROS 产生和 Syk 酪氨酸激酶的途径刺激 NLRP3 炎症小体。
PLoS One. 2010 Apr 2;5(4):e10008. doi: 10.1371/journal.pone.0010008.
2
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.AIM2 炎性小体对于宿主防御细胞质细菌和 DNA 病毒至关重要。
Nat Immunol. 2010 May;11(5):395-402. doi: 10.1038/ni.1864. Epub 2010 Mar 28.
3
Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-kappa B signaling.致病弧菌通过细胞毒素和 TLR/核苷酸结合寡聚结构域介导的 NF-κB 信号通路激活 NLRP3 炎症小体。
J Immunol. 2010 May 1;184(9):5287-97. doi: 10.4049/jimmunol.0903536. Epub 2010 Mar 26.
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Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.李斯特菌被 NLRP3 和 AIM2 炎性小体感知。
Eur J Immunol. 2010 Jun;40(6):1545-51. doi: 10.1002/eji.201040425.
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Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome.结核分枝杆菌蛋白 ESAT-6 是 NLRP3/ASC 炎症小体的有效激活剂。
Cell Microbiol. 2010 Aug;12(8):1046-63. doi: 10.1111/j.1462-5822.2010.01450.x. Epub 2010 Feb 9.
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Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome.通过 NLRC4 炎性小体对 III 型分泌装置的先天免疫检测。
Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3076-80. doi: 10.1073/pnas.0913087107. Epub 2010 Feb 1.
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The inflammasomes: mechanisms of activation and function.炎症小体：激活与功能机制。
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Pore formation triggered by Legionella spp. is an Nlrc4 inflammasome-dependent host cell response that precedes pyroptosis.军团菌属诱导的孔形成是一种依赖于 Nlrc4 炎性体的宿主细胞反应，先于细胞焦亡。
Infect Immun. 2010 Mar;78(3):1403-13. doi: 10.1128/IAI.00905-09. Epub 2010 Jan 4.
9
Thioredoxin-interacting protein links oxidative stress to inflammasome activation.硫氧还蛋白相互作用蛋白将氧化应激与炎症小体激活联系起来。
Nat Immunol. 2010 Feb;11(2):136-40. doi: 10.1038/ni.1831. Epub 2009 Dec 20.
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Involvement of the NLRP3 inflammasome in innate and humoral adaptive immune responses to fungal beta-glucan.NLRP3 炎性小体在真菌β-葡聚糖固有和体液适应性免疫反应中的作用。
J Immunol. 2009 Dec 15;183(12):8061-7. doi: 10.4049/jimmunol.0902477.
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