Department of Radiation Oncology, China Medical University Hospital, and School of Medicine, College of Medicine, China Medical University, No. 2, Yuh-Der Road, Taichung 404, Taiwan.
Cancer Epidemiol Biomarkers Prev. 2011 Mar;20(3):473-5. doi: 10.1158/1055-9965.EPI-10-1280. Epub 2011 Feb 4.
Patients with depression are suggestive of having a tendency toward a marginally significant association with the subsequent cancer risk. The aim of this study was to evaluate the possible relationship between depression and cancer risk in Taiwan.
We used the data of the National Health Insurance system of Taiwan to assess this issue. The Cox proportional hazard regression analysis was conducted to estimate the effects of depression on the cancer risk.
In patients with depression, there was no significant change in the risk of developing overall cancer or for the site-specific cancer and all showed the same direction (positive) except for colorectal cancer, which had a negative direction.
This population-based study did not find Taiwanese patients with depression to have a higher risk to develop overall cancer or site-specific cancer.
Depression does not increase cancer risk.
抑郁症患者表现出与随后的癌症风险有一定关联的倾向。本研究旨在评估台湾地区抑郁症与癌症风险之间的可能关系。
我们使用了台湾全民健康保险系统的数据来评估这个问题。采用 Cox 比例风险回归分析来估计抑郁症对癌症风险的影响。
在患有抑郁症的患者中，总体癌症或特定部位癌症的发病风险没有显著变化，且所有结果均呈现相同的方向（阳性），除了结直肠癌，其方向为阴性。
本基于人群的研究未发现台湾抑郁症患者的总体癌症或特定部位癌症发病风险增加。
抑郁症不会增加癌症风险。
