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年龄相关性黄斑变性(AMD)和斯塔加特病(STGD)中的交互式图像分析

Interactive Image Analysis in Age-related Macular Degeneration (AMD) and Stargardt Disease (STGD).

作者信息

Smith R Theodore, Lee Noah, Chen Jian, Busuioc Mihai, Laine Andrew F

机构信息

Ophthalmology Department, Columbia University, New York, NY 10027 USA.

出版信息

Conf Rec Asilomar Conf Signals Syst Comput. 2008 Oct 26;42:651-654. doi: 10.1109/ACSSC.2008.5074487.

DOI:10.1109/ACSSC.2008.5074487
PMID:21297895
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3033041/
Abstract

The literature of the last three decades is replete with automatic methods for retinal image analysis. Acceptance has been limited due to post-processing or tuning requirements that may be just as time consuming as the original manual methods. The point of view herein is that by taking advantage of the human visual system and expert knowledge from the outset, the promised efficiencies of digital methods can be achieved in practice as well as in theory. Thus, simple labeling of regions of interest that is accepted and easily performed in a few moments by the human can provide enormous advantage to an already well-developed algorithm. Three examples are provided: drusen segmentation, image registration, and geographic atrophy segmentation, with applications to disease understanding.

摘要

过去三十年的文献中充斥着用于视网膜图像分析的自动方法。由于后处理或调整要求可能与原始手动方法一样耗时,其接受度受到限制。本文的观点是,从一开始就利用人类视觉系统和专家知识,数字方法所承诺的效率在实践和理论上都可以实现。因此,人类能够在几分钟内轻松接受并完成的感兴趣区域的简单标记,可为已经成熟的算法带来巨大优势。文中提供了三个例子:玻璃膜疣分割、图像配准和地图样萎缩分割,并将其应用于疾病理解。

相似文献

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引用本文的文献

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Quantitative comparison of drusen segmented on SD-OCT versus drusen delineated on color fundus photographs.在频域光学相干断层扫描(SD-OCT)上分割出的玻璃膜疣与在彩色眼底照片上描绘出的玻璃膜疣的定量比较。
Invest Ophthalmol Vis Sci. 2010 Oct;51(10):4875-83. doi: 10.1167/iovs.09-4962. Epub 2010 Apr 14.

本文引用的文献

1
A novel registration method for retinal images based on local features.一种基于局部特征的视网膜图像配准新方法。
Annu Int Conf IEEE Eng Med Biol Soc. 2008;2008:2242-5. doi: 10.1109/IEMBS.2008.4649642.
2
Autofluorescence characteristics of early, atrophic, and high-risk fellow eyes in age-related macular degeneration.年龄相关性黄斑变性早期、萎缩性和高危对侧眼的自发荧光特征
Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5495-504. doi: 10.1167/iovs.05-1318.
3
Predictive value of fundus autofluorescence for development of geographic atrophy in age-related macular degeneration.年龄相关性黄斑变性中眼底自发荧光对地图样萎缩发生的预测价值。
Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2655-61. doi: 10.1167/iovs.05-1027.
4
Autofluorescence characteristics of normal foveas and reconstruction of foveal autofluorescence from limited data subsets.正常黄斑中心凹的自发荧光特征及从有限数据子集中重建黄斑中心凹自发荧光
Invest Ophthalmol Vis Sci. 2005 Aug;46(8):2940-6. doi: 10.1167/iovs.04-0778.
5
Automated detection of macular drusen using geometric background leveling and threshold selection.利用几何背景均衡和阈值选择自动检测黄斑玻璃膜疣。
Arch Ophthalmol. 2005 Feb;123(2):200-6. doi: 10.1001/archopht.123.2.200.
6
A method of drusen measurement based on reconstruction of fundus background reflectance.一种基于眼底背景反射率重建的玻璃膜疣测量方法。
Br J Ophthalmol. 2005 Jan;89(1):87-91. doi: 10.1136/bjo.2004.042937.
7
Photographic patterns in macular images: representation by a mathematical model.黄斑图像中的摄影模式:用数学模型表示
J Biomed Opt. 2004 Jan-Feb;9(1):162-72. doi: 10.1117/1.1630604.
8
A2E, a byproduct of the visual cycle.A2E,视觉循环的一种副产品。
Vision Res. 2003 Dec;43(28):2983-90. doi: 10.1016/s0042-6989(03)00475-9.
9
A method of drusen measurement based on the geometry of fundus reflectance.一种基于眼底反射几何形状的玻璃膜疣测量方法。
Biomed Eng Online. 2003 Apr 18;2:10. doi: 10.1186/1475-925x-2-10.
10
Fundus autofluorescence in patients with age-related macular degeneration and high risk of visual loss.年龄相关性黄斑变性且有高视力丧失风险患者的眼底自发荧光
Am J Ophthalmol. 2002 Mar;133(3):341-9. doi: 10.1016/s0002-9394(01)01404-0.