Epstein Nancy E
Neurological Surgery, The Albert Einstein College of Medicine, Bronx, NY 10451, and Winthrop University Hospital, Mineola, NY 11501, USA.
Surg Neurol Int. 2011 Jan 24;2:9. doi: 10.4103/2152-7806.76146.
Few studies focus on the fusion rates and outcomes for single-level anterior cervical diskectomy/fusion (1-ACDF) utilizing iliac autograft and dynamic plates.
Fusion rates and outcomes were prospectively evaluated in 60 consecutive patients undergoing 1-ACDF utilizing iliac autograft and dynamic plates (ABC; Aesculap, Tuttlingen, Germany). Eighteen patients had radiculopathy, while 42 were myelopathic (average Nurick Score 3.3). Pathology included single-level disc disease/spondylosis (38 patients) and/or ossification of the posterior longitudinal ligament (OPLL, 22 patients). Fusion was assessed at 3, 6, and up to 12 months postoperatively utilizing dynamic X-rays and 2D-CT scans. Outcomes were evaluated up to 24 months postoperatively utilizing Odom's Criteria, Nurick Grades, and Short-Form 36 (SF-36) outcome questionnaires. Patients were followed for an average of 4.8 postoperative years (minimum 2 years).
Although dynamic X-rays/2D-CT studies documented 100% fusion an average of 3.8 months (range 2.5-8 months] postoperatively, 5 heavy smokers exhibited delayed fusions [6-8 months postoperatively]. Two years postoperatively, the average Nurick Score was 0.3 (mild radiculopathy), while Odom's Criteria revealed 52 excellent, 6 good, and 2 fair outcomes [the latter 8 patients were heavy smokers]). Utilizing SF-36 outcome questionnaires, patients markedly improved (>10.0 point gain) on 5 of 8 Health Scales within 6 months, 7 of 8 within 1 year, and all 8 within 2 postoperative years.
For 60 patients undergoing 1-ACDF utilizing dynamic plates, ultimately a 100% fusion rate was achieved (5 heavy smokers exhibited delayed fusions). Two years postoperatively, Nurick Grades, Odom's Criteria, and SF-36 questionnaires revealed adequate outcomes.
很少有研究关注采用自体髂骨移植和动力钢板进行单节段颈椎前路椎间盘切除融合术(1-ACDF)的融合率及疗效。
对连续60例行1-ACDF并采用自体髂骨移植和动力钢板(ABC;德国图特林根的蛇牌公司)的患者的融合率及疗效进行前瞻性评估。18例患者有神经根病,42例为脊髓病(平均Nurick评分3.3)。病变包括单节段椎间盘疾病/脊椎关节强硬(38例患者)和/或后纵韧带骨化(OPLL,22例患者)。术后3、6及长达12个月时利用动态X线片和二维CT扫描评估融合情况。术后长达24个月时利用奥多姆标准、Nurick分级和简明健康状况调查量表(SF-36)结果问卷评估疗效。患者术后平均随访4.8年(最短2年)。
尽管动态X线片/二维CT研究显示术后平均3.8个月(范围2.5 - 8个月)融合率达100%,但5例重度吸烟者出现延迟融合(术后6 - 8个月)。术后2年,平均Nurick评分为0.3(轻度神经根病),而奥多姆标准显示52例优、6例良、2例可(后8例患者为重度吸烟者)。利用SF-36结果问卷,患者在术后6个月内8个健康量表中的5个显著改善(得分增加>10.0分),1年内8个中的7个显著改善,术后2年内8个全部显著改善。
对于60例行采用动力钢板的1-ACDF的患者,最终融合率达100%(5例重度吸烟者出现延迟融合)。术后2年,Nurick分级、奥多姆标准和SF-36问卷显示疗效良好。