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气压、湿度、太阳辐射、温度和风速对德国巴伐利亚州因慢性阻塞性肺病导致的门诊就诊的影响。

Influence of air pressure, humidity, solar radiation, temperature, and wind speed on ambulatory visits due to chronic obstructive pulmonary disease in Bavaria, Germany.

机构信息

Division of Respiratory Medicine Campus Innnenstadt, Ludwig-Maximilians-Universität Munich, Ziemssenstraße 1, 80336, Munich, Germany.

出版信息

Int J Biometeorol. 2012 Jan;56(1):137-43. doi: 10.1007/s00484-011-0405-x. Epub 2011 Feb 8.

Abstract

Chronic obstructive pulmonary disease (COPD) is one of the most important causes of morbidity and mortality in the world. The disease is often aggravated by periods of increased symptoms requiring medical attention. Among the possible triggers for these exacerbations, meteorological factors are under consideration. The objective of this study was to assess the influence of various meteorological factors on the health status of patients with COPD. For this purpose, the daily number of ambulatory care visits due to COPD was analysed in Bavaria, Germany, for the years 2006 and 2007. The meteorological factors were provided by the model at the European Centre for Medium Range Weather Forecast (ECMWF). For the multivariate analysis, a generalised linear model was used. In Bavaria, an increase of 1% of daily consultations (about 103 visits per day) was found to be associated with a change of 0.72 K temperature, 209.55 of log air surface pressure in Pa, and a decrease of 1% of daily consultations with 1,453,763 Ws m(2) of solar radiation. There also seem to be regional differences between north and south Bavaria; for instance, the effect of wind speed and specific humidity with a lag of 1 day were only significant in the north. This study could contribute to a tool for the prevention of exacerbations. It also serves as a model for the further evaluation of the impact of meteorological factors on health, and could easily be applied to other diseases or other regions.

摘要

慢性阻塞性肺疾病(COPD)是世界上发病率和死亡率的最重要原因之一。该疾病常因症状加重而需要医疗关注而加剧。在这些加重的可能诱因中,气象因素正在考虑之中。本研究的目的是评估各种气象因素对 COPD 患者健康状况的影响。为此,对德国巴伐利亚州 2006 年和 2007 年因 COPD 而进行的日常门诊就诊次数进行了分析。气象因素由欧洲中期天气预报中心(ECMWF)的模型提供。对于多变量分析,使用了广义线性模型。在巴伐利亚,每天咨询量增加 1%(约每天 103 次就诊)与温度变化 0.72K、对数空气表面压力变化 209.55Pa 和每天咨询量减少 1%有关,与 1,453,763Wsm2 的太阳辐射量减少有关。南北巴伐利亚之间似乎也存在区域差异;例如,风速和特定湿度的影响具有 1 天的滞后,仅在北部具有统计学意义。本研究可以为预防加重提供一种工具。它也是进一步评估气象因素对健康影响的模型,并且可以轻松应用于其他疾病或其他地区。

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