Departamento de Genética, Instituto de Biociências, UNESP, Botucatu, SP, Brazil.
J Bioenerg Biomembr. 2011 Feb;43(1):71-9. doi: 10.1007/s10863-011-9336-9.
Mitochondrial inner membrane uncoupling proteins (UCP) catalyze a proton conductance that dissipates the proton electrochemical gradient established by the respiratory chain, thus affecting the yield of ATP synthesis. UCPs are involved in mitochondrial energy flow regulation and have been implicated in oxidative stress tolerance. Based on the global gene expression profiling datasets available for Arabidopsis thaliana, in this review we discuss the regulation of UCP gene expression during development and in response to stress, and provide interesting insights on the possible existence of epigenetic regulation of UCP expression.
线粒体内膜解偶联蛋白 (UCP) 催化质子通过，使呼吸链建立的质子电化学梯度耗散，从而影响 ATP 合成的效率。UCP 参与线粒体能量流的调节，并与氧化应激耐受有关。基于拟南芥的全球基因表达谱数据集，本文讨论了 UCP 基因在发育过程中的表达调控以及对胁迫的响应，并对 UCP 表达的表观遗传调控的存在提供了有趣的见解。
