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洞穴贝氏菌模式菌株(HKI 0122)的全基因组序列

Complete genome sequence of Beutenbergia cavernae type strain (HKI 0122).

作者信息

Land Miriam, Pukall Rüdiger, Abt Birte, Göker Markus, Rohde Manfred, Glavina Del Rio Tijana, Tice Hope, Copeland Alex, Cheng Jan-Fang, Lucas Susan, Chen Feng, Nolan Matt, Bruce David, Goodwin Lynne, Pitluck Sam, Ivanova Natalia, Mavromatis Konstantinos, Ovchinnikova Galina, Pati Amrita, Chen Amy, Palaniappan Krishna, Hauser Loren, Chang Yun-Juan, Jefferies Cynthia C, Saunders Elizabeth, Brettin Thomas, Detter John C, Han Cliff, Chain Patrick, Bristow James, Eisen Jonathan A, Markowitz Victor, Hugenholtz Philip, Kyrpides Nikos C, Klenk Hans-Peter, Lapidus Alla

出版信息

Stand Genomic Sci. 2009 Jul 20;1(1):21-8. doi: 10.4056/sigs.1162.

Abstract

Beutenbergia cavernae (Groth et al. 1999) is the type species of the genus and is of phylogenetic interest because of its isolated location in the actinobacterial suborder Micrococcineae. B. cavernae HKI 0122(T) is a Gram-positive, non-motile, non-spore-forming bacterium isolated from a cave in Guangxi (China). B. cavernae grows best under aerobic conditions and shows a rod-coccus growth cycle. Its cell wall peptidoglycan contains the diagnostic L-lysine ← L-glutamate interpeptide bridge. Here we describe the features of this organism, together with the complete genome sequence, and annotation. This is the first completed genome sequence from the poorly populated micrococcineal family Beutenbergiaceae, and this 4,669,183 bp long single replicon genome with its 4225 protein-coding and 53 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project.

摘要

洞穴贝氏菌(Beutenbergia cavernae)(Groth等人,1999年)是该属的模式种,因其在放线菌亚目微球菌科中的孤立位置而具有系统发育学研究价值。洞穴贝氏菌HKI 0122(T)是一种革兰氏阳性、不运动、不产芽孢的细菌,从中国广西的一个洞穴中分离得到。洞穴贝氏菌在有氧条件下生长最佳,呈现杆状-球菌生长周期。其细胞壁肽聚糖含有特征性的L-赖氨酸←L-谷氨酸肽间桥。在此,我们描述该微生物的特征,以及完整的基因组序列和注释。这是来自物种稀少的微球菌科贝氏菌属的首个完成的基因组序列,这个长度为4,669,183 bp的单复制子基因组及其4225个蛋白质编码基因和53个RNA基因是细菌和古菌基因组百科全书项目的一部分。

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