Rozánek P, Otcenásek M, Steiner I, Mencl K
Nemocnice s poliklinikou OUNZ Pardubice, Ustav experimentální biofarmacie CSAV Hradec Králové.
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl. 1990;33(4):387-95.
Five cases of bronchopulmonary aspergillosis are scrutinized which showed no unambiguous account for any of 6 forms of the disease as described previously. Clinical signs, roentgenograms and bronchoscopy findings testified about the interaction between the aspergillus and the host being in accord with either the aspergilloma or chronical necrotizing pulmonary aspergillosis. Authors preclude the invasive symptomatology represents a developmental and likely initial phase in aspergilloma's onset. Apart from the disease progression, markedly extinctive signs of aspergilloma's activity have in contrast been detected after a period of its duration. In this case, the important signs are associated rather with the occurrence of other microorganisms whose participation was proved in 3 from 5 patients. Authors suggest also the immune status of those affected and the process invasiveness should be taken in mind in providing etiotropic treatment with the impact on the spectrum of microorganisms detected.
对5例支气管肺曲霉菌病病例进行了详细检查，这些病例均未明确符合先前描述的6种疾病形式中的任何一种。临床症状、X线胸片和支气管镜检查结果表明，曲霉菌与宿主之间的相互作用符合曲菌球或慢性坏死性肺曲霉菌病。作者推测侵袭性症状是曲菌球发病的一个发展阶段，可能也是初始阶段。除了疾病进展外，在曲菌球持续一段时间后，反而检测到其活动明显消退的迹象。在这种情况下，重要的迹象与其他微生物的出现有关，5例患者中有3例证实有其他微生物参与。作者还建议，在提供针对检测到的微生物谱的病因治疗时，应考虑患者的免疫状态和疾病的侵袭性。
