Azpiroz F
Digestive System Research Unit, Hospital General Vall d'Hebron, Autonomous University of Barcelona.
Acta Gastroenterol Belg. 1990 Sep-Dec;53(5-6):518-22.
Functional dyspepsia is a clinical syndrome defined by upper abdominal symptoms, without identifiable cause by conventional diagnostic evaluation. New diagnostic tests, such as gastrointestinal manometry and gastric emptying, may help in a better characterization of these patients by demonstrating specific motor abnormalities, such as postprandial antral hypomotility and delayed gastric emptying of solids, or less frequently, intestinal dysmotility patterns indicating a visceral neuropathy. Nevertheless, a substantial proportion of dyspeptic patients have normal motility patterns. Interestingly, recent studies have shown that a gastric hypersensitivity to distension may be the cause of the postprandial symptoms in functional dyspepsia. These data indicate that functional dyspepsia may include an heterogeneous group of patients with different underlying disturbances.
功能性消化不良是一种以上腹部症状为特征的临床综合征，常规诊断评估无法明确其病因。新的诊断测试，如胃肠测压和胃排空试验，通过显示特定的运动异常，如餐后胃窦运动减弱和固体食物胃排空延迟，或较少见的提示内脏神经病变的肠道运动异常模式，可能有助于更好地对这些患者进行特征描述。然而，相当一部分消化不良患者的运动模式正常。有趣的是，最近的研究表明，胃对扩张的超敏反应可能是功能性消化不良餐后症状的原因。这些数据表明，功能性消化不良可能包括一组具有不同潜在紊乱的异质性患者。
