通过 Pd 催化的 2-卤代苯乙炔与 2-炔基苯酚反应高效生成茚并[1,2-c]色烯。
Efficient generation of indeno[1,2-c]chromenes via the Pd-catalyzed reaction of 2-alkynylhalobenzenes with 2-alkynylphenols.
机构信息
Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.
出版信息
Chem Commun (Camb). 2011 May 14;47(18):5298-300. doi: 10.1039/c1cc11169h. Epub 2011 Mar 31.
PMID:21451869
Abstract
A palladium-catalyzed reaction of 2-alkynylhalobenzenes with 2-alkynylphenols in the presence of PCy(3) is discovered, which provides an efficient and facile route to indeno[1,2-c]chromenes. This reaction works efficiently, leading to the corresponding products in good to excellent yields.
摘要
钯催化的 2-卤代苯乙炔与 2-炔基苯酚在三(环己基)膦（PCy(3)）存在下的反应被发现，为茚并[1,2-c]色烯的合成提供了一种高效、简便的途径。该反应效率高，以良好到优秀的产率得到相应的产物。
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