Shimizu Shigetaka, Cureoglu Sebahattin, Yoda Shigetoshi, Suzuki Mamoru, Paparella Michael M
Department of Otolaryngology, Tokyo Medical University, Japan.
Acta Otolaryngol. 2011 Mar;131(3):263-8. doi: 10.3109/00016489.2010.532155.
Blockage of the endolymphatic duct is a significant finding in Meniere's disease. The position of the utriculo-endolymphatic valve (UEV) and blockage of the ductus reuniens in the temporal bones were not found to be directly indicative of Meniere's disease.
Comparison of blockage of the longitudinal flow of endolymph between ears affected by Meniere's disease and normal ears.
We examined 21 temporal bones from 13 subjects who had Meniere's disease and 21 normal temporal bones from 12 controls.
The endolymphatic duct was blocked in five (23%) ears affected by Meniere's disease (p = 0.016). The utricular duct was blocked in 16 (76%) ears affected by Meniere's disease and 11 (52%) normal ears (p = 0.112). The saccular duct was blocked in 6 (28%) of ears affected by Meniere's disease and 16 (76%) normal ears (p = 0.001). The ductus reuniens was blocked in 10 (47%) ears affected by Meniere's disease and 10 (47%) normal ears (p = 1.000).
内淋巴管阻塞是梅尼埃病的一项重要发现。颞骨中椭圆囊-内淋巴管瓣膜（UEV）的位置以及连合管阻塞并未被发现可直接指示梅尼埃病。
比较梅尼埃病患耳与正常耳之间内淋巴纵向流动的阻塞情况。
我们检查了13名患有梅尼埃病的受试者的21块颞骨以及12名对照者的21块正常颞骨。
在5只（23%）梅尼埃病患耳中内淋巴管阻塞（p = 0.016）。在16只（76%）梅尼埃病患耳以及11只（52%）正常耳中椭圆囊管阻塞（p = 0.112）。在6只（28%）梅尼埃病患耳以及16只（76%）正常耳中球囊管阻塞（p = 0.001）。在10只（47%）梅尼埃病患耳以及10只（47%）正常耳中连合管阻塞（p = 1.000）。
