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抗蚊抗体对啮齿类疟原虫伯氏疟原虫感染法氏按蚊的影响。

Effect of anti-mosquito antibodies on the infectivity of the rodent malaria parasite Plasmodium berghei to Anopheles farauti.

作者信息

Ramasamy M S, Ramasamy R

机构信息

Queensland Institute of Medical Research, Herston, Australia.

出版信息

Med Vet Entomol. 1990 Apr;4(2):161-6. doi: 10.1111/j.1365-2915.1990.tb00274.x.

DOI:10.1111/j.1365-2915.1990.tb00274.x
PMID:2132980
Abstract

The effect of mouse anti-mosquito antibodies, present in the bloodmeal, on the infectivity of Plasmodium berghei Vincke to Anopheles farauti Laveran was investigated. Significantly fewer oocysts developed in mosquitoes feeding on mice immunized with sugar-fed mosquito midgut antigens than in mosquitoes feeding on control mice. Mosquitoes feeding on mice immunized with the midgut antigens derived from sugar-fed mosquitoes also showed reduced mortality and had lower infection rates than those fed on unimmunized mice. Blood-fed midgut antigen was less effective in producing these effects than sugar-fed midgut antigen.

摘要

研究了存在于血餐中的小鼠抗蚊抗体对伯氏疟原虫温氏株感染费氏按蚊拉氏亚种的影响。取以食糖喂养的蚊虫中肠抗原免疫的小鼠血液喂食的蚊子,其发育的卵囊数量显著少于取对照小鼠血液喂食的蚊子。取以食糖喂养的蚊虫中肠抗原免疫的小鼠血液喂食的蚊子,与取未免疫小鼠血液喂食的蚊子相比,死亡率降低且感染率更低。取吸食血液后的中肠抗原免疫的小鼠血液喂食的蚊子,在产生这些效果方面不如取食糖喂养的中肠抗原免疫的小鼠血液喂食的蚊子有效。

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